To her Microsoft- guru husband, Bernadette is a fearlessly opinionated partner; to fellow private- school mothers in Seattle, she's a disgrace; to design mavens, she's a revolutionary architect; and to 15- year- old Bee, she's a best friend and, simply, Mom. Bee has aced her report card and claimed her reward: a family trip to Antarctica. For Bernadette, who has become increasingly agoraphobic, such a trip is problematic. Then Bernadette disappears.