Mad scientists have never had it so tough. In super-hero comics, graphic novels, films, TV series, video games, and even works of what may be fiction, they are besieged by those who stand against them, devoid of sympathy for their irrational, megalomaniacal impulses to rule, destroy, or otherwise dominate the world as we know it. Dr. Frankenstein was the first truly mad scientist of the modern era. And what did it get him? Destroyed by his own creation. And Jules Verne’s Captain Nemo, a man ahead of his time as well as out of his head — what did he do to deserve persecution? Even Lex Luthor, by all accounts a genius, has been hindered not once, not twice, but so many times that it has taken hundreds of comic books, a few films, and no fewer than ten full seasons of a television series to keep him properly thwarted.