Powers ( Three Farmers on Their Way to a Dance ; Prisoner's Dilemma ) is a recipient of a MacArthur "genius" grant , and it seems appropriate: this strange, overwritten, often infuriating, manically intelligent and sometimes deeply moving novel could hardly have been produced by a writer of mere talent. Powers has woven an extraordinary knowledge of music, of science (particularly of the search for genetic coding, and of computer programming), of the mysteries of language and art history, into a saga that is dazzling and wearying in almost equal measure. The novel jumps back and forth between the late '50s, when brilliant scientist Stuart Ressler is involved with an Illinois research team trying to break the mysteries of DNA coding, and the '80s, when librarian Jan O'Deigh and computer programmer Franklin Todd get to know Ressler, now holding an insignificant night job at a massive computer database operation in Brooklyn, N.