Set in Troy, New York, this linked collection follows a quirky and resilient family of women throughout the twentieth century.In 1908, Mamie Garrahan faces childbirth aided by her arsenic-eating sister-in-law Kitty, a nun who grows opium poppies, and a doctor who prescribes Bayer Heroin. "In the twentieth century, I believe there are no saints left," Mamie remarks. But her daughters and granddaughter test this notion with far-reaching consequences. Kitty's arsenic reappears sixty years later in the hands of her distraught niece. A schoolgirl's passion for the Beatles and Melville—a passion both lonely and funny—shapes her life. Each decade is illuminated by endearingly eccentric characters: an anorexic waitress falls for a wealthy college boy in the jazz age.